Universidad Catolica has won the Copa Sudamericana once in 2021, making them the first Chilean club to win the tournament.
Union La Calera has never won the Copa Sudamericana but reached the quarterfinals in 2021, their best performance in the competition.
The two clubs have faced each other twice in Copa Sudamericana history, with Universidad Catolica winning one match and the other ending in a draw.
Universidad Catolica is based in Santiago, the capital city of Chile, while Union La Calera is based in La Calera, a town in the Valparaiso region.
Both clubs have a strong fanbase and a rich history in Chilean football, with Universidad Catolica being one of the most successful clubs in the country and Union La Calera known for their attacking style of play.