The most recent meeting between Grimsby Town and Sheffield Wednesday in the EFL Cup took place in August 2019, with Sheffield Wednesday securing a 4-1 victory.
Grimsby Town made their first appearance in the EFL Cup in the 2019-2020 season, while Sheffield Wednesday has a rich history in the competition.
Sheffield Wednesday have reached the semi-finals of the EFL Cup on four occasions, most recently in the 1992-1993 season.
Grimsby Town have never advanced past the second round of the EFL Cup in their history.
The largest margin of victory between Grimsby Town and Sheffield Wednesday in the EFL Cup was a 3-0 win by Grimsby in October 2001.